How to save 51B lives for 68 cents with simple Engineering

we look back those are the egg sacs oh I'm not kidding oh my god my bills I have in my hand a microscope that is waterproof stomp proof I put it together in two minutes and it costs fifty

cents

to make and In this hand I have a blood centrifuge which has been ten times faster than a ten thousand dollar centrifuge and costs 18 cm. Both were invented here at Stanford in the laboratory of a brilliant physicist-biologist inventor named Prakash with the goal of helping. improve the

lives

of the world's poorest through a scalable, profitable and incredibly low-cost invention its sleeve of the estimated 100 billion people who have lived on this planet more than half have died of malaria the symptoms are similar to those of the flu until the gold standard for diagnosis is spinning a drop of blood in a centrifuge and then looking at it under a microscope.

Historically, this has been very difficult to do in the places that need it most because the equipment can cost tens of thousands of dollars and the electricity that these two inventions can generate. diagnosing malaria costs less than a dollar and requires no electricity less good to finally meet you absolutely you are like a superhero I don't know about that an

engineering

perspective what you do is amazing before we move on to the new thing let me support that statement by showing you how this microscope really works of 50 cent paper, so it comes like this and then you take out the pieces of paper and then you follow

simple

instructions like folding origami, the lens is actually a small glass sphere embedded in this plastic, you abandon your slide the year and then you look at through that little glass sphere and it's magnified 140 times.

You can even bring your phone closer and film and then capture a video like this. Your lab at Stanford. What are you doing? What is your mission? Of this high level. I grew up in India and one of the things I've always enjoyed is being exposed to scientific tools. When I started the lab, it was very clear that we were missing this hunger for scientific research, so we were almost fifty percent part-time. building and designing scientific tools under the umbrella really finds out that it can't cost a ton of money because every 0 that is added to a scientific event probably hundreds and thousands and millions and billions of people get cut off.

I wanted to try the paper microscope so we got a spoonful of seemingly clear water from this pond and there was a small white spot that didn't settle to the bottom of our bag when he suggested we look closer, they can send suction well and they run away like If it flies and you're trying to duck it, it feels your hand coming before it comes and that's what's really happening, it realizes you know, like it's about to jump into a fish's mouth, it runs away, But I think I'll catch it. You've got it there, okay, oh, it's perfect, remember with the naked eye, you can barely see this tiny white, those are the single eyes, you see that dot, yeah, right there and then we look back, those are the eggs in the back.

Oh, no kidding. Oh, this could be 10 to 15 eggs. 25 those are the hemorrhage, but when I said that when I was sucking it with adrenaline, that's the fresh air variation to go, it's crazy, you know, this reminds me of IAM like the first time I saw the stars. with the telescope, yes, sure, so you can see the stars all the time and even see images of the stars, but until you actually see them, yes, yourself in a telescope, it's like something moves inside you and I feel that we are doing the same. But the other way around, I think it's such a beautiful analogy.

Well, with this 50 cent paper microscope you can see any malaria in your blood. We usually think of blood as a red liquid, but it is actually full of particles like white red blood cells. Blood cells and platelets for the problem are just a couple of drops of blood, you have a billion red blood cells, so like the needle in a haystack it tries to fight off some that have come out of malaria, that's where those few come in , you take some blood and put it in the tube and the particles will mix like that, but when you spin it very fast for a couple of minutes, some incapable force pushes all the heavier particles to the outside and displaces the less dense particles towards the middle, so when you stop All the particles are carefully arranged from the most dense edge to the least dense in the center and you find a red blood cell infected with malaria.

It is a little less dense than a healthy one, you will always find it between the healthy red blood cells and the clear ones. plasma, that is, centrifuges are really critical, so I went to the latest customer news, colleagues Dobbs, to see how they apply their Google scientific philosophy. There is usually very expensive equipment. These are traditional centrifuges that consume a quarter of electricity and you can see how. It's huge, imagine if you had a stroller on your back, if you're in limited research sitting in India, for example, when I grew up, then if you want to do this, you can't use something like this, which costs thousands of dollars. dollars and it requires electricity, so while we were out there we had full scope, but you couldn't just think of blood or urine or feces and do it, that again became the basis of the design problem statement that he came up with: I want something. probably less than a dollar, preferably made of lightweight materials like paper so it's easy to carry in your pocket.

It must match the speeds of these devices. Think about different gears and mechanisms when you walk into your kitchen and backyard and start thinking about toys. Stories are the gateway, so we started looking at yo-yo egg beaters and others have thought about salad spinners. What we found in this world of energy leakage by chance is that it is one of the most efficient ways to convert your energy into rotational energy and it was. At the time, aha, I said use the train as a drive right in the middle instead of mechanical gears or I was just trying this out and as soon as I saw that in 10 seconds, in the back of your mind you know this is something powerful and already You know, transitions beyond a toy are something that has really important applications in global health, so let's recreate that moment, we're going to take some blood and we just need to spin it, we need to figure out what's okay, so if you're spending just for 10 seconds at 20,000 rpm you can see that my blood was already separating there is my own blood I have never seen my blood at our level before here we go each one of those is a flood zone what I like most about renewing the grass If their childlike fascination and curiosity about the world around them, they are also incredibly observant and look for ways in which their

engineering

talents uniquely help or inspire others.

It is a contagious and refreshing optimism. I want to thank Bill and Melinda Gates for collaborating with me on this video. If you'd like to learn more about how life has improved and will continue to improve at Worldport, check out the annual letter from Bill and Melinda Gates. I'll leave a link in the video description. It is a fascinating region. You will get an idea of ​​their ambitious goals. It is the future with zero cases of diseases like malaria, polio and television. If you watch the news, it may seem like the world is becoming a crappier place, so the truth is that poverty rates and infant mortality rates for the world's poorest have completely plummeted. in the last 15 years and this is partly due to people like less and those and support them thank you for seeing the two examples of this, that's right, I'm awake, yes, that's two more early mornings for me at zero Walker, that's my ally, love.

It is an extreme case if it is 9 in the morning and I got pregnant a lot.