Counting red cells on an impedance based blood counter

Hi, This animation will describe how weight

cells

are counted and measured using the

impedance

method that was first described by Wallace Scooter back in the 1950s. This technique is still employed in many of the automated mythology analyzers that are available. on the market even until now. The culture

counter

takes advantage of the change in electrical resistance that occurs when a particle passes through an opening separating two chambers containing a conductive fluid. In this case, a particle is aligned and passed through the opening at the same time as an electric current such as red. The cell passes through the opening, creating a change in resistance and therefore

impedance

.

This change in impedance is proportional to the volume of red

blood

cell passing through it. The pulses and the size of the pulse wave are integrated and fed into a computer that can plot them. the data of a histogram of this histogram when the number of events can be counted, which is the count of velocity

cells

for a given volume, the average value of the histogram provides an estimate of the average size of the velocity cells, this is known on average The cell volume or mcb cells with the smallest diameter would appear as events that are to the left of the histogram, i.e. being low mcb, while the largest house will be plotted to the right of the histogram and this would appear as high mcv, therefore, a low mcv. would denote microcytosis while a high mcv would denote macrocytosis a large variation in cell size with small cells and large cells entering the detection zone will result in a histogram with a very spread appearance using statistical methods the computer can calculate the degree of variation

based

on the standard deviation of the graph and this is known as rate distribution with an increase in rdw would denote red

blood

cells and isocytosis